碱性亮氨酸拉链转录因子的翻译后修饰在植物响应非生物胁迫中的作用

Role of post-translational modification of basic leucine zipper transcription factors in response to abiotic stresses in plants

摘要:

非生物胁迫是植物生长发育过程中必须要应对的不利环境因素。在进化过程中，植物获得了多种响应或抵抗逆境的能力，其中转录因子在调控非生物胁迫耐受性方面起到了重要作用。碱性亮氨酸拉链转录因子(basic leucine zipper transcription factors, bZIP)是转录因子中较大的基因家族之一。不同的翻译后修饰(post-translational modifications, PTMs)可以控制bZIP转录因子的稳定性和活性，响应各种细胞内或细胞外胁迫。本文介绍了bZIP转录因子的结构特征与分类，重点综述了bZIP转录因子磷酸化、泛素化和小泛素相关修饰物(small ubiquitin-like modifier, SUMO)化等翻译后修饰在植物响应非生物胁迫中的作用，并对未来的研究方向进行了展望，为通过调控bZIP转录因子的翻译后修饰培育优良抗逆作物品种提供研究参考。

Abstract:

Abiotic stresses substantially affect the growth and development of plants. Plants have evolved multiple strategies to cope with the environmental stresses, among which transcription factors play an important role in regulating the tolerance to abiotic stresses. Basic leucine zipper transcription factors (bZIP) are one of the largest gene families. The stability and activity of bZIP transcription factors could be regulated by different post-translational modifications (PTMs) in response to various intracellular or extracellular stresses. This paper introduces the structural feature and classification of bZIP transcription factors, followed by summarizing the PTMs of bZIP transcription factors, such as phosphorylation, ubiquitination and small ubiquitin-like modifier (SUMO) modification, in response to abiotic stresses. In addition, future perspectives were prospected, which may facilitate cultivating excellent stress-resistant crop varieties by regulating the PTMs of bZIP transcription factors.