蛋白质交联用酶的作用机制及研究进展

Mechanisms and applications of enzyme-catalyzed protein cross-linking

摘要:

蛋白质交联在食品、化工和医药等领域发挥重要的作用。利用酶催化蛋白质交联是一种可替代物理和化学交联的高效经济的方法。然而,目前仍缺乏详细的酶促蛋白质交联分子层面的解析。本文综述了酶催化的蛋白质交联反应机制及其对蛋白质结构的影响,以及在食品、化工和医药领域的应用,并展望了酶促交联的发展。

Abstract:

Protein cross-linking plays important roles in food, chemical, medicine and other fields.Enzyme-catalyzed protein cross-linking is an efficient and economically viable alternative to physical and chemical cross-linking. However, detailed analysis of enzyme-catalyzed protein cross-linking at molecular level is still lacking. This review summarized the mechanisms of enzyme-catalyzed protein cross-linking,its effects on protein structure, and its applications in food, chemical and pharmaceutical fields.