Abstract:In recent years, antibiotics have been widely used in animal husbandry, aquaculture and the medication in China. Many antibiotics are discharged into the environment, resulting in dramatic increase of antibiotic residues in domestic water and soil. Residues of different antibiotics in the environment change the microbial structure, which is extremely harmful to the ecological environment and humans. Therefore, remediation of antibiotic contamination is significantly important. Studies have shown that some microorganisms can degrade and utilize antibiotics, and thus have good application prospects on bioremediation of antibiotic contamination. However, little is known about the microbial degradation mechanism of antibiotics. This article summarizes the removal of antibiotics by antibiotic-degrading strains and bacterial flora in recent ten years, and the methods of using microbial flora to treat antibiotic residues. The future prospect of using microbial remediation to reduce antibiotic residues in the environment has also been discussed.