组学技术在核盘菌研究中的应用

Application of omics approaches in Sclerotinia sclerotiorum

摘要:

核盘菌Sclerotinia sclerotiorum是一种典型的死体营养型植物病原真菌，全球分布且寄主范围广泛，严重危害多种植物，对农业生产造成严重损失。核盘菌研究主要集中在真菌生物学及病理学等方面。近年来，随着高通量分析技术的不断改进，多种组学技术为系统生物学研究提供了平台。文中主要综述利用多种组学研究方法在植物病原真菌核盘菌研究中的应用及研究进展，探讨开展植物病原物及病害发展的系统性研究思路，以期为核盘菌的分子生物学及致病机理等研究提供参考，同时也为其他植物病原物及病害系统研究提供理论依据。

Abstract:

Sclerotinia sclerotiorum is a typical necrotrophic plant pathogenic fungus that distributes worldwide and causes severe diseases on a broad-range of plant species. Studies on S. sclerotiorum have been mainly focused on biology and pathology. The development of high-throughput technologies enabled multi-omics approaches for systems biology. This review summarizes current researches on S. sclerotiorum and proposes systemic strategies for understanding its biology and pathology, to provide novel insights and references for further investigation on molecular biology and pathogenesis of the pathogenic fungi and the pathosystems.