Progress in outer membrane vesicles derived from Klebsiella pneumoniae

Abstract:

Klebsiella pneumoniae is a prevalent clinical conditional pathogen. K. pneumoniae infection involves a complicated network of pathogen-host interactions. Despite the profound knowledge about the molecular and cellular mechanisms of this bacterium, studies remain to be carried out regarding the outer membrane vesicles (OMVs) derived from K. pneumoniae and their role in bacterial pathogenesis. We summarized the current knowledge on the components of OMVs derived from K. pneumoniae and reviewed the research progress in the roles of OMVs in the survival and pathogenicity of K. pneumoniae.

Key words:Klebsiella pneumoniae;outer membrane vesicles;biological function;vaccine