Bacterial surface display is an important biotechnology that involves expressing exogenous target proteins, peptides, or other biomolecules on the surface of bacterial cells to better realize their functions. This technology has been applied in various fields such as biocatalysis, bioremediation, biosensors, and vaccine design. This article first introduces the surface display systems of both Gram-negative and Gram-positive bacteria and summarizes the main host bacteria and anchored proteins currently known. It then reviews the latest research progress in the applications of bacterial surface display in bioremediation. Finally, this paper summarizes the limitations of bacterial surface display in application and makes an outlook on the future research directions, aiming to expand the specific applications of this technology in bioremediation practice.
WANG Xu, XU Wei, ZHOU Ningyi, DING Junmei. Bacterial surface display and research progress in applications of this technology in environmental remediation[J]. Microbiology China, 2024, 51(6): 1854-1872
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