Strategies for improving the efficiency of precise gene editing in filamentous fungi

Abstract:

The application of gene editing enables the efficient and accurate genome modification of filamentous fungi. However, the actual operation is influenced by a variety of factors, which result in low efficiency of precise gene editing mediated by homologous recombination. In this review, we summarize the current methods to improve the precision editing efficiency of filamentous fungi, so as to improve the application of gene editing in strain modification.