Research progress in microbial markers associated with pancreatic cancer

Abstract:

Among all digestive system tumors, pancreatic cancer is characterized by a high degree of malignancy and a low survival rate of patients. However, the specific mechanism of pancreatic cancer remains unclear. As the research on human microorganisms including intestinal microflora is flourishing in recent years, the potential pathogenesis of microorganisms about pancreatic cancer has become a hot topic of research. In this paper, we introduced the microbial markers associated with pancreatic cancer, analyzed their roles in pancreatic cancer, and expounded the effects of the tumor microenvironment formed by microorganisms on pancreatic cancer. This article provides a reference for the further study of the relationship between microorganisms and pancreatic cancer and facilitates the early examination, early prevention, and clinical treatment of pancreatic cancer by using microbiological technology in the future.

Key words:microbiota;pancreatic cancer;tumor microenvironment