Research status and prospects of marine actinomycetes

Abstract:

[Background] Actinomycetes exhibit rich genetic and functional diversity and produce a wide range of secondary metabolites, which play a role in clinical medicine, agricultural production, and pollution control. Marine actinomycetes have attracted much attention due to their special metabolic pathways and their ability to produce unique active natural products. [Objective] To investigate the research hotspots and future trends of marine actinomycetes and provide reference for subsequent research. [Methods] The articles about marine actinomycetes were retrieved from Web of Science with marine actinomycetes or marine actinobacteria as the keyword for quantitative analysis. VOSviewer was used for the visual analysis of the keywords, countries, institutions, authors, and publishing dates. [Results] The total number of articles about marine actinomycetes was increasing year by year. China and the United States far exceeded other countries in the number of articles and the frequency of citations. The relevant studies focused on the isolation and identification of strains, the mining of active natural products, and bioinformatics. [Conclusion] Marine actinomycetes have attracted increasing attention worldwide. Domestic and overseas institutions should strengthen cooperation and employ bioinformatics to further mine the active secondary metabolites and facilitate the development of marine actinomycetes.