Research progress of matrix-assisted laser desorption ionization time-of-flight mass spectrometry in microbial identification

Abstract:

Compared with traditional techniques for microbial identification, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is an accurate, reliable, and rapid technology for identification and typing. We reviewed the relevant research papers in recent years and summarized the latest research progress. MALDI-TOF MS has great advantages in the identification of clinical pathogenic microorganisms, foodborne microorganisms, and environmental microorganisms, which accelerates the process of microbial identification. Furthermore, we explored the latest progress and challenges of this technology in new fields, aiming to provide reference for the development of MALDI-TOF MS in China.