Latest research progress in virulence genes and regulatory networks of Ralstonia solanacearum species complex

Abstract:

Plant bacterial wilt is a soil-borne disease that can cause huge economic losses. The pathogen, Ralstonia solanacearum species complex (RSSC), can synthesize virulence factors through a complex virulence regulatory network and secrete them into the intercellular matrix or cytoplasm of plant cells, thereby causing disease and withering of host plants. This paper elaborates on the main virulence genes and regulatory networks of RSSC, including the motility (flagella and fimbriae), bacterial secretion systems (T2SS, T3SS, and T6SS), virulence regulatory systems (Phc, Prh, Vsr, Peh, and Sol), virulence factors (CWDEs, T3Es, and EPS), the quorum sensing signal AHL, and phytohormones. We summarized the latest research progress and depicted the relevant regulation network, aiming to provide a reference for further research on the pathogenic mechanism of plant bacterial wilt.