Effect of microorganisms in intestinal tract and urinary system on the pathogenesis of renal calculus:a review

doi:10.13344/j.microbiol.china.211230

Home > Archive>Volume 49, Issue 9, 2022 >3967-3978. DOI:10.13344/j.microbiol.china.211230

Effect of microorganisms in intestinal tract and urinary system on the pathogenesis of renal calculus:a review
DOI:
                        10.13344/j.microbiol.china.211230
                    
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                        32113.14.j.MC.211230
                    
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                        HE ChunyanHE Chunyan
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, China
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ZHANG NingnanZHANG Ningnan
Department of Urology, The First Peoples Hospital of Yunnan Province, Kunming 650034, Yunnan, China;Department of Urology, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650034, Yunnan, China
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YANG MinYANG Min
Department of Urology, The First Peoples Hospital of Yunnan Province, Kunming 650034, Yunnan, China;Department of Urology, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650034, Yunnan, China
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LIU ChenjianLIU Chenjian
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, China
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LI XiaoranLI Xiaoran
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, Yunnan, China
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SHEN JieSHEN Jie
Department of Urology, The First Peoples Hospital of Yunnan Province, Kunming 650034, Yunnan, China;Department of Urology, The Affiliated Hospital of Kunming University of Science and Technology, Kunming 650034, Yunnan, China
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Abstract:

Renal calculus, a common urinary disorder in adults, influences the physiological function of the kidney and leads to urinary tract infection, thus threatening human health. Renal calculi are surrounded by a diversified microbial community, and the changes of microorganisms in the intestinal tract and urinary system may cause the occurrence and development of renal calculus. Particularly, Bifidobacterium, Lactobacillus, and Enterobacteriaceae are closely related to the occurrence of this disease. This review focused on the role of microorganisms in intestinal tract and urinary system in the formation of renal calculi. In addition, we also introduced the kidney-gut axis, influence of intestinal microorganisms on renal calculus from the production of short-chain fatty acids, the change of oxalate, and the occurrence of inflammation, and the prevention and treatment of this renal disease.

Key words:renal calculus;pathogenesis;microorganisms in urinary system;intestinal microorganisms;kidney-gut axis

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HE Chunyan, ZHANG Ningnan, YANG Min, LIU Chenjian, LI Xiaoran, SHEN Jie. Effect of microorganisms in intestinal tract and urinary system on the pathogenesis of renal calculus:a review[J]. Microbiology China, 2022, 49(9): 3967-3978

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Received:December 27,2021
Revised:June 17,2022
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Online: August 30,2022
Published: September 20,2022

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