Control of persisters:a review

Abstract:

Persisters, a subgroup of bacteria that can survive high dosage of antibiotics, make it more difficult to treat infections with antibiotics and threaten human life and health. How to control and remove persisters has become a research hotspot at the moment. In this paper, we summarize the characteristics and harms of persisters, analyze the formation mechanism of them, and sum up methods for controlling and removing this subgroup. This review is expected to guide the control of persisters and the treatment of persistent infection.