Principle and Technology of Fermentation Engineering is a core course of Biology major in colleges and universities of science and engineering, which has been widely applied. Traditional teaching method mainly based on offline teaching is not conducive to students' mastery of knowledge. Additionally, there are some problems in the experimental teaching of this course, such as delay in updating fermentation equipment, lack of large-scale process equipment and site restrictions, which seriously affect the teaching quality. Hybrid teaching mode incorporating online and offline teaching is an important means to enrich teaching resources and improve teaching quality. Taking process and practice of antibiotic production by fermentation as an example, we constructed a virtual simulation experiment project on the basis of virtual simulation platform. In addition, combining offline teaching methods such as classroom teaching and laboratory teaching, we formed a new hybrid teaching mode highly integrating online and offline teaching. The hybrid teaching strengthened the organic combination of classroom teaching and online teaching, as well as virtual and physical experiment, which facilitated students' mastery of theoretical knowledge and experimental skills, cultivated their innovative spirit and practical ability, and improved their comprehensive quality.
LI Qichang, BAN Yihui, XU Zhouying, XIE Hao, LI Yuan, CHEN Bifeng. Mixed teaching of Principle and Technology of Fermentation Engineering: an example of process and practice of antibiotic production by fermentation[J]. Microbiology China, 2022, 49(4): 1245-1254
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