Microorganisms exist widely in nature, and the interactions between microorganisms have an important impact on community structure and function. At present, great attention has been paid to the mechanism of microbial interactions, and the important genes affecting the growth of an individual microorganism in the interactions have been identified by high-throughput genome sequencing and statistical analysis. In order to further study the genetic mechanism of microbial interactions, the role of genes related to motility, drug resistance, nutrient absorption and metabolic regulation in Escherichia coli under the interaction conditions was reviewed in this paper. The genetic mechanism of interactions among Escherichia coli and other microorganisms was discussed from these aspects. In general, these genes are very important for the survival of E. coli. These studies enhance our understanding of the mechanism of bacterial interactions, and lay a theoretical foundation for the future study of more complex genetic mechanisms of microbial community interactions.
LI Beibei, ZHU Hanzhao, ZHANG Qi, YANG Peng, JIN Yi, HE Xiaoqing. Research progress in important genes affecting microbial interactions: take Escherichia coli as an example[J]. Microbiology China, 2021, 48(9): 3071-3082
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