Research progress of Cpx two-component system in bacteria

Abstract:

Bacteria can grow in the environment that other microorganisms can't survive, so it must have more powerful ability to adapt to the external environment. The efficiency of cell signal transduction determines the rate and ability of bacteria to respond to external stimulus. Two-component system is an important structure to maintain the survival of bacteria under conditions of stress. Two-component system Cpx is widely distributed in Gram-negative bacteria, which plays a major role in responding to the changes of external environment and making adaptive response. In this paper, the types of two-component signal transduction system in bacteria, the regulation of Cpx two-component system, the regulated target genes by Cpx two-component system and their physiological behavior were briefly reviewed to provide ideas and theoretical guidance for further research.