Home > Archive>Volume 48, Issue 8, 2021 >2870-2880. DOI:10.13344/j.microbiol.china.200771
PDF HTML XML Export Cite reminder
Research progress in resources mining and polyphase classification of myxobacteria
Author:
  • Article
    • | |
  • Metrics
    • |
  • Reference [28]
    • |
  • Related [20]
    • | | |
  • Comments
    Abstract:

    Myxobacteria are a kind of medical microorganisms that could produce abundant secondary metabolites, show complex multicellular behaviors and prey kinds of bacteria and fungi. Therefore, myxobacteria have important values of research and application. However, it seriously impedes myxobacterial mining and utilization because of their difficulties to isolate, cultivate, and research in polyphase classification. This review described myxobacterial features, methods for isolation and purification, and discussed existing problems and improvement measures. In addition, we also analyzed the research status in polyphase classification of myxobacteria. Based on the current technical means and research progress, the future research trends of myxobacteria were prospected. This review aims to provide help to relevant researches on myxobacteria in the future.

    Reference
    [1] Li SG, Zhou XW, Wu ZH, Li YZ. Population ecology and survival strategy of myxobacteria[J]. Microbiology China, 2013, 40(1):172-179(in Chinese)李曙光, 周秀文, 吴志红, 李越中. 粘细菌的种群生态及其生存策略[J]. 微生物学通报, 2013, 40(1):172-179
    [2] Kaiser D, Kroos L. Intercellar signaling[A]//Dworkin MKD. Myxobacteria Ⅱ[M]. Washington DC:Am Soc Microbiol, 1993:257-283
    [3] Wenzel SC, Müller R. Myxobacteria-'microbial factories' for the production of bioactive secondary metabolites[J]. Molecular BioSystems, 2009, 5(6):567-574
    [4] Mohr KI. Diversity of myxobacteria-we only see the tip of the Iceberg[J]. Microorganisms, 2018, 6(3):84
    [5] Garcia RO, Reichenbach H, Ring MW, Müller R. Phaselicystis flava gen. nov., sp. nov., an arachidonic acid-containing soil myxobacterium, and the description of Phaselicystidaceae fam. nov.[J]. International Journal of Systematic and Evolutionary Microbiology, 2009, 59(6):1524-1530
    [6] Garcia R, Pistorius D, Stadler M, Müller R. Fatty acid-related phylogeny of myxobacteria as an approach to discover polyunsaturated omega-3/6 fatty acids[J]. Journal of Bacteriology, 2011, 193(8):1930-1942
    [7] Mohr KI, Zindler T, Wink J, Wilharm E, Stadler M. Myxobacteria in high moor and fen:an astonishing diversity in a neglected extreme habitat[J]. MicrobiologyOpen, 2017, 6(4):e00464
    [8] Gerth K, Pradella S, Perlova O, Beyer S, Müller R. Myxobacteria:proficient producers of novel natural products with various biological activities-past and future biotechnological aspects with the focus on the genus Sorangium[J]. Journal of Biotechnology, 2003, 106(2/3):233-253
    [9] Li ZF, Li X, Liu H, Liu X, Han K, Wu ZH, Hu W, Li FF, Li YZ. Genome sequence of the halotolerant marine bacterium Myxococcus fulvus HW-1[J]. Journal of Bacteriology, 2011, 193(18):5015-5016
    [10] Albataineh H, Stevens DC. Marine myxobacteria:a few good halophiles[J]. Marine Drugs, 2018, 16(6):209
    [11] Reichenbach H, Lang E, Schumann P, Spröer C. Byssovorax cruenta gen. nov., sp. nov., nom. rev., a cellulose-degrading myxobacterium:rediscovery of 'Myxococcus cruentus' Thaxter 1897[J]. International Journal of Systematic and Evolutionary Microbiology, 2006, 56(10):2357-2363
    [12] Sanford RA, Cole JR, Tiedje JM. Characterization and description of Anaeromyxobacter dehalogenans gen. nov., sp. nov., an aryl-halorespiring facultative anaerobic myxobacterium[J]. Applied and Environmental Microbiology, 2002, 68(2):893-900
    [13] Garcia R, Müller R. Simulacricoccus ruber gen. nov., sp. nov., a microaerotolerant, non-fruiting, myxospore-forming soil myxobacterium and emended description of the family Myxococcaceae[J]. International Journal of Systematic and Evolutionary Microbiology, 2018, 68(10):3101-3110
    [14] Yamamoto E, Muramatsu H, Nagai K. Vulgatibacter incomptus gen. nov., sp. nov. and Labilithrix luteola gen. nov., sp. nov., two myxobacteria isolated from soil in Yakushima Island, and the description of Vulgatibacteraceae fam. nov., Labilitrichaceae fam. nov. and Anaeromyxobacteraceae fam. nov.[J]. International Journal of Systematic and Evolutionary Microbiology, 2014, 64:3360-3368
    [15] Weissman KJ, Müller R. A brief tour of myxobacterial secondary metabolism[J]. Bioorganic & Medicinal Chemistry, 2009, 17(6):2121-2136
    [16] Bian XY, Tang B, Yu YC, Tu Q, Gross F, Wang HL, Li AY, Fu J, Shen YM, Li YZ, et al. Heterologous production and yield improvement of epothilones in burkholderiales strain DSM 7029[J]. ACS Chemical Biology, 2017, 12(7):1805-1812
    [17] Hoffmann T, Krug D, Bozkurt N, Duddela S, Jansen R, Garcia R, Gerth K, Steinmetz H, Müller R. Correlating chemical diversity with taxonomic distance for discovery of natural products in myxobacteria[J]. Nature Communications, 2018, 9:803
    [18] Bader CD, Panter F, Müller R. In depth natural product discovery-Myxobacterial strains that provided multiple secondary metabolites[J]. Biotechnology Advances, 2020, 39:107480
    [19] Tautz T, Hoffmann J, Hoffmann T, Steinmetz H, Washausen P, Kunze B, Huch V, Kitsche A, Reichenbach H, Höfle G, et al. Isolation, structure elucidation, biosynthesis, and synthesis of antalid, a secondary metabolite from Polyangium species[J]. Organic Letters, 2016, 18(11):2560-2563
    [20] Li YZ, Li J, Zhou L, Zhang Y, Hu W, Chen Q. Isolation and identification of myxobacteria[J]. Acta Microbiologica Sinica, 2000, 40(6):652-656(in Chinese)李越中, 李建, 周璐, 张勇, 胡玮, 陈琦. 我国粘细菌(Myxobacteria)资源的分离与鉴定[J]. 微生物学报, 2000, 40(6):652-656
    [21] Yan ZC, Wang B, Li YZ, Gong X, Zhang HQ, Gao PJ. Morphologies and phylogenetic classification of cellulolytic myxobacteria[J]. Systematic and Applied Microbiology, 2003, 26(1):104-109
    [22] Zhang XJ, Yao Q, Cai ZP, Xie XL, Zhu HH. Isolation and identification of myxobacteria from saline-alkaline soils in Xinjiang, China[J]. Plos One, 2013, 8(8):e70466
    [23] Zhang XJ, Lv YY, Zhu HH. Isolation and identification of myxobacteria in virgin forest of Vietnam[J]. Current Biotechnology, 2018, 8(2):147-152(in Chinese)张鲜姣, 吕颖颖, 朱红惠. 越南原始森林粘细菌的分离与鉴定[J]. 生物技术进展, 2018, 8(2):147-152
    [24] Zhao ZY, Zhang XJ, Tan ZY, Guo J, Zhu HH. Isolation and identification of cultivable myxobacteria in the rhizosphere soils of medicinal plants[J]. Acta Microbiologica Sinica, 2013, 53(7):657-668(in Chinese)赵智颖, 张鲜姣, 谭志远, 郭俊, 朱红惠. 药用植物根系土壤可培养粘细菌的分离鉴定[J]. 微生物学报, 2013, 53(7):657-668
    [25] Li BY, Xie XL, Zhang XJ, Cai ZP, Zhu HH. Influence of different prey strains on isolation of myxobacteria in saline-alkaline soils of Xinjiang[J]. Acta Microbiologica Sinica, 2013, 53(4):379-389(in Chinese)李百元, 谢小林, 张鲜娇, 蔡卓平, 朱红惠. 不同被捕食细菌对新疆盐碱地粘细菌分离的影响[J]. 微生物学报, 2013, 53(4):379-389
    [26] Zhang XJ, Lv YY, Zhu HH. Study on diversity of cultivable myxobacteria in wetland environment[J]. Current Biotechnology, 2018, 8(2):140-146(in Chinese)张鲜姣, 吕颖颖, 朱红惠. 湿地环境可培养粘细菌多样性研究[J]. 生物技术进展, 2018, 8(2):140-146
    [27] Shimkets LJ, Dworkin M, Reichenbach H. The myxobacteria[A]//Dworkin M, Falkow S, Rosenberg E, et al. The Prokaryotes[M]. New York:Springer, 2006:31-115
    [28] Fudou R, Jojima Y, Iizuka T, Yamanaka S. Haliangium攠牯湣獨?潡晣?浵慭爠楧湥敮?洠祮硯潶戮愬挠瑳数爮椠慮汯?椮猠潡汮慤琠效獡孬?嵡???灵灭氠楴敥摰?慤湵摭??湰瘮椠牮潯湶洮攺湮瑯慶汥??業捯牤潥扲楡潴汥潬杹礠???はば???????????????????扩牳?孬??嵥?娠桦潲畯?堠坣???楴?卬????楩?坥???楶慩湲杯??????慛湊????坯畵?婮????楦?奇婥???祡硬漠扡慮捤琠敁牰楰慬汩?捤漠浍浩畣湲楯瑢祩?楬獯?慹?瀠爲攰搰漲洬椠渴愸渨琲?愺渱搰?栭椱朱栵氼祢?搾楛瘲改牝猠敍?扨慲挠瑋敉爬椠慓汴?杣牨潬畩灮?椠湍?猠潗楩汮?渠楊挬栠敗獩孬?嵡???湅瘬椠牓潴湡浤敬湥瑲愠汍??楃捯牭潰扡楲潩汳潯杮礠?剦攠灭潹牸瑯獢???づ???????????????扡牮?嬠??嵡??敡慴湩敯?删???敩牳汯敬浡慴湩????呵档散?灳牳攠摩慮琠潴牷祯?汮楩晣敨?捳示捋汩敲?潴晩??祴硩漠捉潳捬捡畮獤?硡慮湤琠桇略獲孭?嵮???業捰牯潳扴楛潊汝漮朠祍???は????????????????戶爬?嬵??崩?圲愶游札′?????瘾?夳夰???楡??婤??央愠潂?兯???敹渠条?????婯桢畡??????畲汩瑢畵牴敩?摮攠灯敦渠摭敹湸瑯?慡湣摴??楩湡搠敩灮攠湳摯敩湬瑳?浊敝琮栠潆摅獍?爠敍癩散慲汯敢摩?慬湯?慹戠畒湥摶慩湥瑷?洬礠砲漰戰愰挬琠攲爴椨愴氩?挴漰洳洭甴渲椷琼祢?猾桛愳瀱敝搠?扩礠?潙琬栠教牡?戠慑挬琠敚牨極愠?慈渮搠?灰??楯湡??椠湴杯栠畡獮桡慬湹?慥挠楴摨楥挠?獩潶楥汲獳孩?嵹??偦?潭卹?佯湢敡???ひ?ち????????攠ぢ???????扮牥?孴??崠??慒爭捤楥慮?剴???敮浧瀠敧牲污敤楩湥???????????汴汲敯牰?副???楩湳椠挨祄獇瑇楅猩?牢潡獳敥慤?杯敮渠??湸潯癮???獥灣??湩潣瘠???慥?灊潝氮礠畐湬獯慳琠畏牮慥琬攠搲‰昱愴琬琠礹?愱挰椩携?爱椰挸核?愷渼摢?猾瑛攳爲潝椠摙?瀠牓潘搬甠捚楨湯杵?獙漬椠汚?浡祮硧漠托慊挬琠教牡楯甠浑嬬?嵌???湐琬攠牚湨慵琠楈潈渮愠汅??潥畣牴湳愠汯?漠晤?卦祦獥瑲敥浮慴琠楩捳?慬湡摴??癮漠汭略瑴楨潯湤慳爠祯??楦捲牵潩扴楩潮汧漠杢祯??㈠て????????ㄠ????????????扥牲?孡?㈠嵩??睬慡汴?副偮???愮爠捁楣慴?删?????????汯汧敩牣?删??剮慩捣敡洬椠挲礰猲琱椬猠?挱爨漴挩攺愹′朳攭渹??渨潩癮???獩灮??湥漩瘼???愼?獢漾榁況?洬礠硨潨戬愠挠璜旣爬椠痚浒?椠湎?瑳栬攠?暢懠洮椠氍礌?傻澹法秹慐溞杓楢愐掌斘懆旌嬆?嶄???湊瑝攮爠溮感瑩楦澥測愠氲‰?漱甬爠渶愱氨?漩昺?匲礳猭琹攳洴愼瑢楲挾?愳渳摝??癩漠汓畇琬椠潚湨慯牵礠??椬挠牌潩戠楐潆氬漠杈祡????ㄠ???????????????????戠牌?嬠??崮??楨癥椠湥杸獩瑳潴湥敮?健????渠杤汩敶扥祲?佩???楯牦搠睭潹潸摯?卡???潲潩歡猠潩湮??剡???潭牵灤栺敡眠?割???坯桵楳瑬睹漠牵瑮桥?????健牤攠摭慹瑸潯牢祡?潴牥杲慩湡椠獨浡獢?睴楡瑴桛?畝渮琠慅灮灶敩摲?扮業潥獮祴湡瑬栠敍瑩楣捲?灢潩瑯敬湯瑧楹愠汒?摰敯獲捴牳椬瀠琲椰漱渲猬?漴昨?温漺瘵攸氷??漹爵愼汢汲漾捛漳挴捝甠獗?獮灧攠捘楈攬猠????愬戠敘物祡猠瑙眬礠瑗桥敮渠獘楈猬?獄灩??渠潋瘮??????捥慱牵浥慮牣瑩桮敧渠獡楮獡?獹灳??渠潯癦??????敲硩敡牬挠楤瑩當獥?獳灩??渠潩癮??????楳湴瑥敷牡整浥灲琠潴牲?獡灴??湮潴瘠???????氠慩湮猠瑃敨晩普慡湛敊湝献椠獁?獰灬??湤漠癡??????灩牲慯敮摭慥瑮潴牡?猠灍??湲潯癢??????猬椠挲愰爱椲甬猠?猸瀨??温漺瘷??′愭渷搰????瑲放牛洳椵湝愠瑇潲物?獥瀠??測漠癋?孮?崠???瀠灃汯楮敬摡?愠湓搬??湥癭楩牮潧渠浃敂測琠慄污??楳挠牊漬戠楙潯汮潧朠祁??㈠あ?ふ?????㈠??攬??????扳牬?孹??嵗??桍慵浲扲敡特猠????升灲慥牥歮猠?乄??卥祴搠湡敬礮?乔???楧癲楡湰杨獩瑣潡湬攠?偮????潭潰歯獲潡湬??剩??坲桳楩瑴睹漠牯瑦栠??????潭浡灮愠牳慫瑩楮瘠敭?杣敲湯潢浩楯捭獥?慊湝搮?灓慣湩?杮散湥漬洠椲挰猰?漬映″琲栴攨‵?礳砱漩挺漱挱挹愰挭攱愱改??楢湲挾汛申搶楝渠杗?慮?搠敂猬挠版極瀠瑗椬漠湌?潵映?昬椠癚敨?湮潧瘠敃汙?猠灚敨捡楯攠獊??礠硊潩捡潮捧挠畄獍?攠癗敵爠獚潈爬?獌灩??湚漮瘠????祴硡潴捩潯据挠畯獦?汳污慬湴昭慴楯牬灥睲污汮杴眠祍湹杸祯汣汯杣潣杵敳爠祳捴桲睡祩牮湳搠牡潮扤眠汴汨?汩汲愠湭瑯祴獩楬汩楴潹朠潳杹潳杴潥捭桳攠湴獯椠獴?獥瀠??湥潡癮????祤硩潴捩潯据捳畛獊?瘮愠獍瑩慣瑲潯牢?獡灬??湣潯癬???倬礠砲椰搰椷挬漠挵挴用猱?挺愴攳爭昵礱爼摢摲椾湛攳渷獝椠獚?獡灮??湙潑瘬???愠湙摚?倠祗硡楮摧椠捂漬挠捗畵猠?瑈爬甠捚楨摡慮瑧漠牃?猬瀠??湮潧瘠?嬬?嵑???敚湊漬洠敚??楮潧氠潙朮礠?慨湡摲??癴潥汲畩瑳楴潩湣???の????????㈠?????????　??戀爀?嬀??崀??栀甀渀????伀爀攀渀????嘀攀渀琀漀猀愀?????栀爀椀猀琀攀渀猀攀渀?????爀愀栀愀氀??刀??搀愀??漀猀琀愀??匀??刀漀漀渀攀礀??倀??夀椀????堀甀?堀圀??搀攀??攀礀攀爀?匀???攀琀?愀氀??倀爀漀瀀漀猀攀搀?洀椀渀椀洀愀氀?猀琀愀渀搀愀爀搀猀?昀漀爀?琀栀攀?甀猀攀?漀昀?最攀渀漀洀攀?搀愀琀愀?昀漀爀?琀栀攀?琀愀砀漀渀漀洀礀?漀昀?瀀爀漀欀愀爀礀漀琀攀猀嬀?崀???渀琀攀爀渀愀琀椀漀渀愀氀??漀甀爀渀愀氀?漀昀?匀礀猀琀攀洀愀琀椀挀?愀渀搀??瘀漀氀甀琀椀漀渀愀爀礀??椀挀爀漀戀椀漀氀漀最礀???　??????????????????戀爀?嬀??崀??漀搀攀?????刀椀渀最??圀??匀挀栀眀?愀甀洀氀?爀?????爀漀瀀瀀攀渀猀琀攀搀琀?刀????愀椀猀攀爀???????????氀氀攀爀?刀????栀礀搀爀漀砀礀???洀攀琀栀礀氀最氀甀琀愀爀礀氀?挀漀攀渀稀礀洀攀?????漀???猀礀渀琀栀愀猀攀?椀猀?椀渀瘀漀氀瘀攀搀?椀渀?戀椀漀猀礀渀琀栀攀猀椀猀?漀昀?椀猀漀瘀愀氀攀爀礀氀??漀??椀渀?琀栀攀?洀礀砀漀戀愀挀琀攀爀椀甀洀??礀砀漀挀漀挀挀甀猀?砀愀渀琀栀甀猀?搀甀爀椀渀最?昀爀甀椀琀椀渀最?戀漀搀礀?昀漀爀洀愀琀椀漀渀嬀?崀???漀甀爀渀愀氀?漀昀??愀挀琀攀爀椀漀氀漀最礀???　　?????????????????????戀爀?嬀??崀??愀爀挀椀愀?刀???攀爀琀栀????匀琀愀搀氀攀爀?????漀最洀愀??爀????????????氀氀攀爀?刀???砀瀀愀渀搀攀搀?瀀栀礀氀漀最攀渀礀?漀昀?洀礀砀漀戀愀挀琀攀爀椀愀?愀渀搀?攀瘀椀搀攀渀挀攀?昀漀爀?挀甀氀琀椀瘀愀琀椀漀渀?漀昀?琀栀攀??甀渀挀甀氀琀甀爀愀戀氀攀猀?嬀?崀???漀氀攀挀甀氀愀爀?倀栀礀氀漀最攀渀攀琀椀挀猀?愀渀搀??瘀漀氀甀琀椀漀渀???　?　????????????????戀爀?嬀??崀??椀甀?夀??夀愀漀?儀??娀栀甀??????攀琀愀???匀?爀刀一??最攀渀攀?瀀栀礀氀漀最攀渀攀琀椀挀?爀攀挀漀渀猀琀爀甀挀琀椀漀渀?爀攀瘀攀愀氀猀?琀栀攀?愀猀琀漀渀椀猀栀椀渀最?搀椀瘀攀爀猀椀琀礀?漀昀?挀漀猀洀漀瀀漀氀椀琀愀渀?洀礀砀漀戀愀挀琀攀爀椀愀嬀?崀???椀挀爀漀漀爀最愀渀椀猀洀猀???　??????????????戀爀?嬀??崀??挀?甀爀搀礀?????匀琀甀搀椀攀猀?漀渀?琀栀攀?琀愀砀漀渀漀洀礀?漀昀?琀栀攀?洀礀砀漀栀愀挀琀攀爀愀氀攀猀?????爀攀挀漀爀搀?漀昀?挀愀渀愀搀椀愀渀?椀猀漀氀愀琀攀猀?愀渀搀?猀甀爀瘀攀礀?漀昀?洀攀琀栀漀搀猀嬀?崀???愀渀愀搀椀愀渀??漀甀爀渀愀氀?漀昀??椀挀爀漀戀椀漀氀漀最礀?????????????????????????戀爀?嬀?　崀?圀愀爀甀搀攀?????漀猀栀椀?????愀爀猀甀氀欀愀爀????倀漀氀礀甀渀猀愀琀甀爀愀琀攀搀?昀愀琀琀礀?愀挀椀搀猀?戀椀漀琀攀挀栀渀漀氀漀最礀嬀?崀???爀椀琀椀挀愀氀?刀攀瘀椀攀眀猀?椀渀??椀漀琀攀挀栀渀漀氀漀最礀???　　???????????????戀爀?嬀??崀??椀甀?夀???愀椀?儀???匀栀愀漀?娀娀???攀渀漀洀攀?戀愀猀攀搀?愀渀愀氀礀猀椀猀?爀攀瘀攀愀氀猀?琀栀攀?琀愀砀漀渀漀洀礀?愀渀搀?搀椀瘀攀爀猀椀琀礀?漀昀?琀栀攀?昀愀洀椀氀礀??搀椀漀洀愀爀椀渀愀挀攀愀攀嬀?崀???爀漀渀琀椀攀爀猀?椀渀??椀挀爀漀戀椀漀氀漀最礀???　????????????????戀爀?嬀??崀??椀甀?夀???愀椀?儀?????漀甀洀氀?欀攀爀?????攀椀攀爀??漀氀琀栀漀昀昀??倀??圀愀渀最????匀甀渀?夀???圀愀渀最????匀栀愀漀?娀娀???攀渀漀洀椀挀?椀渀猀椀最栀琀猀?椀渀琀漀?琀栀攀?琀愀砀漀渀漀洀椀挀?猀琀愀琀甀猀?漀昀?琀栀攀??愀挀椀氀氀甀猀?挀攀爀攀甀猀?最爀漀甀瀀嬀?崀??匀挀椀攀渀琀椀昀椀挀?刀攀瀀漀爀琀猀???　???????????　???戀爀?嬀??崀???漀甀洀氀?爀搀琀???????????瀀攀稀??????攀椀攀爀??漀氀琀栀漀昀昀??倀??匀挀栀氀攀甀渀椀渀最????圀攀椀渀栀漀氀搀?????吀椀渀搀愀氀氀??????爀漀渀漀眀?匀???礀爀瀀椀搀攀猀?一???圀漀礀欀攀?吀????漀甀洀氀?欀攀爀?????渀愀氀礀猀椀猀?漀昀???　　　??琀礀瀀攀?猀琀爀愀椀渀?最攀渀漀洀攀猀?猀甀戀猀琀愀渀琀椀愀氀氀礀?椀洀瀀爀漀瘀攀猀?琀愀砀漀渀漀洀椀挀?挀氀愀猀猀椀昀椀挀愀琀椀漀渀?漀昀??氀瀀栀愀瀀爀漀琀攀漀戀愀挀琀攀爀椀愀嬀?崀???爀漀渀琀椀攀爀猀?椀渀??椀挀爀漀戀椀漀氀漀最礀???　?　????????
    Cited by
    Comments
    Comments
    分享到微博
    Submit
Get Citation

WANG Chunling, Lü Yingying, YAO Qing, LI Anzhang, ZHU Honghui. Research progress in resources mining and polyphase classification of myxobacteria[J]. Microbiology China, 2021, 48(8): 2870-2880

Copy
Share
Article Metrics
  • Abstract:598
  • PDF: 1290
  • HTML: 2479
  • Cited by: 0
History
  • Received:July 24,2020
  • Adopted:December 19,2020
  • Online: July 30,2021
Article QR Code
  • WeChat ID
  • Mobile Terminal

Microbiology China ® 2025 All Rights Reserved