Research progress on peptides produced by microorganisms

Abstract:

Microbial peptide secondary metabolites, which usually contain rare amino acids, are a series of natural products with rich chemical structures and biological activities. With the development of separation and purification technologies, a great number of new peptide products have been discovered, which play an important role in the exploration of microbial natural products. This paper reviews the microbial peptide metabolites from bacteria and fungi, as well as the new peptide products obtained by gene mining and other bioengineering methods in recent years. Combined with our team's research experiences of peptide products from entomopathogenic nematode symbiotic bacteria, this paper analyzes the existing problems and possible solutions in the research of microbial peptide products. We hope it could provide a reference for the further exploration and application of new active peptide products.