Spore wall structure and its synthesis-associated genes in Saccharomyces cerevisiae: a review

Abstract:

The cell wall is a characteristic structure of yeast cells that distinguishes them from mammalian cells. The structural composition, synthesis and regeneration of the yeast cell wall are closely related to self-reproduction and the response to environmental stress. At present, the mechanism of spore wall formation, regulation processes and the function of spore wall synthesis-associated genes remain elusive. This article briefly describes the process of spore wall formation in Saccharomyces cerevisiae. The spore wall consists of the mannan layer, glucan layer, chitosan layer and dityrosine layer. We summarize genes involved in synthesis of these layers. The purpose of this study is to provide a reference for new antifungal drug target research.