Epitope analysis and vaccine development of severe acute respiratory syndrome coronavirus 2: a review

Abstract:

Vaccination has been considered as the most effective method to prevent the further spread of the current corona virus disease 2019 (COVID-19). Nowadays, many research teams world wide have applied different technologies for the research on the vaccines of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This article summarizes the research on multiple aspects, including epitope analysis of SARS-CoV-2, research progress of vaccines and potential risk of vaccination. It discusses the difficulties in the development and application of vaccines in the meantime of evaluating the safety and effectiveness of the vaccines in the respective research routes.