Progress in the application of electronic circular dichroism technology in the structural study of microbial secondary metabolites

Abstract:

The chemistry construction of microbial secondary metabolites is complex, and the determination of their absolute configuration is very difficult. In recent years, electronic circular dichroism (ECD) has been used more and more in the determination of absolute configuration due to its advantages of low dosage and high accuracy, and it has become an important method to study the structure of microbial secondary metabolites. In this paper, the application of ECD in the structure of microbial secondary metabolites was reviewed, which laid a foundation for future research.

Key words:Microbial secondary metabolites, Absolute configuration, Electronic circular dichroism