Epidemic status and control strategies of bovine viral diarrhea in China

Abstract:

The prevalence of bovine viral diarrhea (BVD) in China remains to be known due to the complicated BVDV infections , and its etiology BVDV (BVDV-1 and BVDV-2) is not limited to infect cattle, also goes to other animal infections including swine BVDV infection which could clinically confuse the classic swine fever monitoring and diagnosis, led to exacerbate the disease course. Due to persistent infection (PI) caused by bovine viral diarrhea virus (BVDV), the eradication of the disease is faced with great difficulty and poses a severe threat to the healthy development of the whole dairy farm. Considering currently there are 22 subtypes of BVDV-1 and 4 subtypes of BVDV-2 for the rapid antigen variation and evolution rate of BVDV, our effective prevention and control of this disease is far behind the viral mutation rate. Therefore, the epidemic status of BVDV-1 and BVDV-2 in pigs and cattle in China is regularly investigated and understood, which is the first and critical step of epidemic disease eradication. To be based on the successful experience of BVD eradication abroad, to comprehensively consider the national conditions, to take appropriate prevention and control strategies, and to gradually eradicate the pathogen infection and the related disease, which is conducive to promote the healthy development of domestic breeding industry.

Key words:Bovine viral diarrhea virus, Subtype, Variation and evolution, Epidemic status