Application of microbial transformation technology in the development of Chinese medicine

Abstract:

The modernization is the most urgent to traditional Chinese medicine research. Microbial biotransformation can help to solve many difficult problems of traditional Chinese medicine research. The article summarizes the characteristics of microbial biotransformation, enzyme systems and reaction types, and analyze the influence of Chinese medicine microbial biotransformation. The conclusions were that the enzyme systems had widely variability, strong selectivity, mild and controllable reaction conditions, multiple reaction types to all active ingredients of traditional Chinese medicine, and the technology was very suitable for the daily and industrial production. After biotransformation, the effects of drugs can be improved, reduce the toxicity, remove the impurities, help to the metabolism in vivo and produce new drug ingredients. The Chinese medicine combinated with microbiology model will significantly promote the modernization of traditional Chinese medicine process.