Quorum sensing: an auto regulator for bacterial pathogenicity

Abstract:

Bacteria could sense the signal molecules and regulate their physiological behavior via quorum sensing (QS). QS is involved in the regulation of biofilm formation, virulent genes expression as well as the phages infection. QS could control adaptive immunity through the regulation of CRISPR-Cas systems, which is the latest finding and presumed to be the highlight in the near future. To elucidate its regulating mechanisms and reveal broad prospect for bacterial therapy by phage, we reviewed QS regulating mechanisms on bacterial pathogenicity for the control of pathogenic bacteria.