Advances of RNA virus increasing viral infection through the exosomes

Abstract:

Exosome is a kind of vesicles secreted by cells. It has been thought to be a new important way of cell and cell communication due to its carrying some molecules such as protein, lipid and nucleic acid. RNA viruses, such as HIV-1, HCV, as a class of important pathogens affect human health. Viruses can promote their replication and transmission using certain relevant functions of the exosomes, however, the relevant study of the interaction of exosome and virus infection has just been started. Many aspects of the exosomes have not been fully recognized and still many studies need to be done. In this paper, we summarize the role of exosome in the promotion of various RNA viruses infection to provide insight into the relationship between RNA viruses and exosomes.