Small non-coding RNAs in Staphylococcus aureus-a review

Abstract:

Staphylococcus aureus is a leading pathogen threatening global public health. Various clinical infections caused by S. aureus are closely related to the expression of many virulence factors. The expression of these virulence factors is precisely regulated by regulatory factors, which have the key role in the pathogenicity of S. aureus. Small non-coding RNAs (sRNAs) are important regulatory factors, which can make S. aureus respond to environmental changes, and regulate the stress and expression of virulence. However, biological functions have only been elucidated for a few of these sRNAs. In this review, we summarize the recent research progress in S. aureus regulatory sRNAs.

Key words:Staphylococcus aureus, Small non-coding RNA, Gene regulation