Ameliorating alcoholic liver injury by adjusting intestinal flora with probiotics

Abstract:

Many clinical trials showed that chronic alcohol leads to imbalance of intestinal flora which is characterized by the decrease of Bifidobacterium and Lactobacillus, with a proportional increase of gram-negative bacteria. Alcohol causes the destruction of intestinal barrier function, increases intestinal permeability, releases bacteria endotoxins, and causes liver damage. This paper reviews the research progress in using probiotics to repair alcoholic liver injury by adjusting the intestinal flora and improving intestinal barrier function.

Key words:Alcoholic liver damage, Intestinal flora, Probiotics