Advances in studies of FluG-BrlA pathway involved in asexual developmental mechanisms of Aspergillus nidulans

Abstract:

Aspergillus nidulans is a filamentous fungus used as a model system for asexual developmental mechanisms study. Taking research of the FluG-BrlA pathway involved in Aspergillus nidulans asexual developmental as the starting point, we summarized current understanding of the asexual developmental including the central regulatory pathway genes (brlA, abaA and wetA), the central regulatory pathway modifiers (stuA and medA) and the central regulatory pathway activators (fluG, flbA?E), as well as the genetic model for related genes of Aspergillus nidulans conidiation. This review can be used as references for researching asexual developmental mechanisms of other filamentous fungi.

Key words:Aspergillus nidulans, Asexual developmental, brlA, Central regulatory pathway, Activators