[Objective] The cluster analysis was applied to the optimization of the Flavomycin flask fermentation. [Methods] The data of Flavomycin flask fermentation from different batches was clustered by using system cluster, K-means cluster and fuzzy C-means cluster. The result showed that fuzzy C-means cluster was better than the other two. [Results] Then the classes were separated and the excellent samples were distilled, moreover, the range of control parameter of Flavomycin flask fermentation was optimized. [Conclusion] The experiment results indicated that cluster analysis was effective in the optimization of fermentation process.
WU Jia-Xin, ZHANG Guo-Dong, LIU Xiao-Jie, QI Peng, ZHENG Ying-Hua, HE Ji-Hong, SONG Min, GE Xin-Mei, WANG Hua-Li, CAO Qin. Application of cluster analysis on Flavomycin fermentation[J]. Microbiology China, 2012, 39(6): 0865-0871
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