Biodegradable PLGA [poly(lactide-co-glycolide acid)] have shown significant potential for sustained and targeted delivery of several pharmaceutical agents, including DNA. We reviewed the formulating approaches of PLGA nanoparticles/microspheres as DNA carriers and utilization for gene therapy and vaccine adjuvant.
WANG Gang, PAN Li, ZHANG Yong-Guang. Research Progress on PLGA Nanoparticles/Microspheres as DNA Carriers[J]. Microbiology China, 2009, 36(12): 1901-1908
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