Advances in Viral Infection Proteomics

Abstract:

Viral invasion will modify the patterns of host cell protein expression, which may affect the normal physiological function of host cell and determines viral pathogenic progress and consequence. Therefor, studies on viral infections proteomics contributes to uncover the mechanism of interaction between virus and host and viral molecular pathogenesis, found early biomarker of virus infection, develop earlier diagnostic method, evaluate therapeutic effect and prognosis and so on. In this paper, techniques of viral infection proteomics, the progress of changes of host cell proteome induced by virus, and serum differential proteome of host after viral infection were introduced.

Key words:Virus, Infection, Proteomics