Integrin and Foot-and-mouth Disease Virus Infection

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Integrin and Foot-and-mouth Disease Virus Infection
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                        DU Jun-ZhengDU Jun-Zheng
National Foot-and-mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046
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CHANG Hui-YunCHANG Hui-Yun
National Foot-and-mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046
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GAO Shan-DianGAO Shan-Dian
National Foot-and-mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046
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CAI Xue-PengCAI Xue-Peng
National Foot-and-mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046
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Abstract:

Integrins are a family of cell surface glycoproteins that contribute to a variety of biological functions, including cell growth, migration, proliferation and morphology. In addition, integrins also play the important roles in pathological process. Several viruses have been showed to use integrins as receptors or co-receptors to infect host cells.This article mainly reviews the progress on integrins and their roles in FMDV infection.

Key words:Integrin， Foot-and-mouth disease virus， Cellular receptor

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DU Jun-Zheng, CHANG Hui-Yun, GAO Shan-Dian, CAI Xue-Peng. Integrin and Foot-and-mouth Disease Virus Infection[J]. Microbiology China, 2007, 34(5): 0960-0964

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