Research advances in the bioactive secondary metabolites from lichen-derived actinomycetes

Abstract:

Actinomycetes are essential sources of secondary metabolites with diverse chemical structures and bioactivities. Lichen is a unique system of fungi and algae. In addition to lichenized fungi and algae, there are also a large number of endophytic fungi and actinomycetes in the lichen ecosystem, which have garnered increasing attention due to their unique ability to produce secondary metabolites. It is of great significance to study the secondary metabolites of lichen-derived actinomycetes for the discovery of active lead compounds and the development and utilization of medicinal microbial resources. This article reviews the research progress in the secondary metabolites and activities of lichen-derived actinomycetes in recent 30 years.

Key words:lichen-derived actinomycetes;secondary metabolites;bioactivity