Abstract:With rich connotation and wide extension, Microbiology provides the theoretical basis and practical guidance in the cultivation of talents majoring in biological, food, and pharmaceutical sciences in colleges and universities. However, the current teaching mode of Microbiology is not suitable for the training goals of talents targeted at the development needs of national and regional industries. This study incorporated the concept of artificial intelligence, which has developed rapidly in recent years, into the teaching of Microbiology, creating an intelligent teaching mode characterized by “trinity of intelligence” (integration of intelligence into the teaching contents, evaluation of whole-process intelligent teaching, and progressive cultivation of intelligent thinking) of Microbiology. This teaching mode gradually improves students’ intelligent thinking and helps to achieve the goal of fostering innovative and application-oriented talents.