Abstract:The teaching of Microbiology Experiments encountered the problems such as the failure to emphasize the center role of students, difficulty in cultivating students' innovative thinking, inability to stimulate students' learning enthusiasm, and inappropriate assessment methods that fail to reflect students' actual abilities. In response to these problems, we have designed the open experiments in Microbiology to arouse students' interests, encourage their participation, and enhance their innovation capability. A three-stage teaching design of Microbiology Experiments was adopted, involving literature research, experimentation, and result summary. This approach enables us to establish a comprehensive assessment plan and achieve the teaching objectives. Additionally, it enriches the professional practice teaching system that is closely linked to theoretical teaching and features the combination of basic, integrated, and innovative teaching. The implementation of open experiments has enhanced students' study skills, research training and project practice, and improved the level of innovation capability in participating in competitions. In addition, open experiments place higher requirements on teachers' research literacy and teaching ability. Proper laboratory management is necessary to ensure the smooth implementation of open experiments.