Abstract:Creating advanced, innovative, and challenging core courses is essential for cultivating high-level talents. Scientific and intelligent teaching methods serve as a guarantee for achieving teaching objectives. Microbial Physiology is a compulsory course offered to the undergraduates in the biological science and experimental science programs. Over a five-year period of core course development, we have established a systematic knowledge framework with distinctive characteristics of agricultural university programs. Following the teaching approach of "translating knowledge into scientific research" and employing diversified assessment methods, we aim to enhance students' understanding, analysis, evaluation, and integrated application of knowledge. The course has become a source of inspiration and ingenious ideas for students' research practices, thereby empowering the cultivation of high-level talents.