Abstract:The new requirement was presented for the training of environmental professionals in universities to foster environmental engineers under the background of ecological conservation. They must have environmental awareness and can quickly diagnose eco-environmental problems and adopt effective and cost-effective technologies to solve these problems. As a core course of the environmental engineering major, the Environmental Engineering Microbiology in Guizhou University was innovated in terms of the professional knowledge, teaching content and the blended teaching method. They include "heuristic preview before class-answering difficult questions in class-classroom flipping-enhancing understanding by immersive practice". Furthermore, diversified assessment methods were adopted throughout the whole process. The innovation significantly improved the teaching achievement of Environmental Engineering Microbiology in Guizhou University.