Abstract:[Background] Microbiota is closely related to the occurrence and development of lung cancer, and the field of study has become a hotspot. [Objective] This study seeks to conduct a comprehensive bibliometric analysis of the literature elucidating the associations between microbiota and lung cancer. Its aims include unveiling the present research status, identifying future trends, and offering a compass for subsequent investigations. [Methods] Literature data were sourced from the Web of Science Core Collection (WOSCC), China National Knowledge Infrastructure (CNKI), Wanfang Data, and VIP database for Chinese technical periodicals (VIP) databases. Furthermore, we used CiteSpace and VOSviewer to visualize the annual publications, countries/regions, and keywords. [Results] A total of 143 Chinese-language publications and 278 English-language publications were included. Notably, China stood out as the most prolific contributor. Keywords analysis showed that lung cancer, gut microbiota, and immunotherapy were research hotspots in this field. [Conclusion] In the past two decades, the vital role of microbiota in the etiology, diagnosis, and treatment of lung cancer has been recognized. Through the comparison of these databases, we found that the hot topics in this field are essentially the same in domestic and foreign. However, this field remains in the early stage, characterized by relatively immature studies and a lack of extensive, close international collaboration. Future studies on the frontier hotspots in this sector need to be strengthened much more. The findings of this study are helpful for researchers to better understand the frontier hotspots and development trends in this area, and provide a reference for the in-depth exploration of future research.
