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微生物学通报

胰腺癌相关微生物标志物研究进展
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Research progress in microbial markers associated with pancreatic cancer
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    摘要:

    在所有消化系统肿瘤中,胰腺癌的恶性程度很高,患者生存率极低,而胰腺癌发病的具体机制尚不明确。随着近年来包括肠道菌群在内的人体微生物研究的迅速发展,微生物在胰腺癌的潜在发病机制也成为研究热点。本文介绍了与胰腺癌相关的微生物标志物,并分析各种微生物标志物对胰腺癌的作用机制以及微生物形成的肿瘤微环境对胰腺癌的影响,为微生物与胰腺癌关系的进一步研究提供参考,有利于学界未来利用微生物相关技术开展胰腺癌的早期检查、早期预防和临床治疗。

    Abstract:

    Among all digestive system tumors, pancreatic cancer is characterized by a high degree of malignancy and a low survival rate of patients. However, the specific mechanism of pancreatic cancer remains unclear. As the research on human microorganisms including intestinal microflora is flourishing in recent years, the potential pathogenesis of microorganisms about pancreatic cancer has become a hot topic of research. In this paper, we introduced the microbial markers associated with pancreatic cancer, analyzed their roles in pancreatic cancer, and expounded the effects of the tumor microenvironment formed by microorganisms on pancreatic cancer. This article provides a reference for the further study of the relationship between microorganisms and pancreatic cancer and facilitates the early examination, early prevention, and clinical treatment of pancreatic cancer by using microbiological technology in the future.

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焦嘉澎,朱柏恒,李堂桦,许宁宁,陈容平. 胰腺癌相关微生物标志物研究进展[J]. 微生物学通报, 2023, 50(11): 5110-5123

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历史
  • 收稿日期:2023-03-26
  • 最后修改日期:
  • 录用日期:2023-06-10
  • 在线发布日期: 2023-11-06
  • 出版日期: 2023-11-20