Abstract:Interspecific electron transport is of great significance to geobiochemical cycles and environmental pollution remediation since it can promote microbial co-metabolism. Interspecies electron transfer can be classified into direct interspecies electron transfer (DIET) and mediated interspecies electron transfer (MIET) according to the mode of electron transfer, in which the former has received extensive attention owing to its common occurrence and high efficiency. This study summarized the research progress in interspecies electron transfer, elaborated the involved pathways, compared the advantages and disadvantages between DIET and MIET, and suggested to mine more microorganisms with interspecies electron transfer function. This review aims to improve understanding of interspecies electron transfer and provide a reference for the future research in this field.