灵芝液态发酵胞内外多糖的研究进展

Liquid fermentation of Ganoderma lingzhi for intracellular and extracellular polysaccharides: a review

摘要:

灵芝具有悠久的药用历史，其活性物质灵芝多糖具有广泛的药理活性，利用液态发酵技术获取灵芝多糖展现出独特优势。近年来，关于灵芝多糖液态发酵的研究报道越来越多，引起了研究者的广泛关注。本文从灵芝多糖的生物合成代谢及调控、液态发酵的培养基及工艺优化等方面对近期的研究结果进行总结，以期为灵芝液态发酵制备胞内外多糖及其产业化应用提供参考和依据。

关键词:灵芝;液态发酵;生物合成;胞内多糖;胞外多糖

Abstract:

Ganoderma lingzhi has long been used as medicine and the active components polysaccharides have extensive pharmacological activities. Liquid fermentation shows unique advantages in extracting G. lingzhi polysaccharides. In recent years, there has been an explosion of research on the liquid fermentation of G. lingzhi to yield polysaccharides, and this technology has attracted the interest of scholars. We summarized the research on the biosynthesis and biosynthesis regulation of G. lingzhi polysaccharides, the optimization of the medium for and process of liquid fermentation, among others, hoping to provide a reference and basis for liquid fermentation of G. lingzhi to yield intracellular and extracellular polysaccharides and its industrial application.

Key words:Ganoderma lingzhi;liquid fermentation;biosynthesis;intracellular polysaccharide;extracellular polysaccharide