Abstract:The application of the "five-stage" flipped classroom teaching model assisted by Blackboard platform in experimental teaching was explored based on the characteristics of research experimental teaching and related theories of blended teaching. The Microbiology Experimental Technology course was used as an example to expound the design thought of the teaching model, i.e., independent learning and experimental design before class, student discussion in class, implementation of open experiment, class presentation, and summary after class. The teaching effects of this model and existing problems were also discussed. The findings may provide reference for the application of flipped classroom teaching model in practical courses, in hope of cultivating students' scientific thinking and innovation ability.