肠道病毒D68受体研究进展

Enterovirus D68 receptors：a review

摘要:

肠道病毒D68型属于小核糖核酸病毒科，近年来在全球范围内呈规律性流行趋势，已成为严重危害公共卫生安全的问题。然而目前尚缺乏针对肠道病毒D68的特效疫苗和药物，对肠道病毒D68的分子致病机理研究仍在不断深入。本文主要对肠道病毒D68病毒受体相关研究进展进行综述，为靶向性抗病毒药物研究提供参考。

关键词:肠道病毒D68;病毒受体;病毒入侵;组织嗜性

Abstract:

Enterovirus D68 (EV-D68), a member of Picornaviridae, has emerged over the recent years, with large outbreaks worldwide. However, no specific vaccines and drugs against EV-D68 are available. Accumulating studies are extending our understanding on the pathogenesis of EV-D68. In this review, we summarized the research on EV-D68 receptors, hoping to provide a reference for the development of targeted antiviral drugs.

Key words:Enterovirus D68;virus receptor;virus entry;tissue tropism