Abstract:Enterovirus D68 (EV-D68), a member of Picornaviridae, has emerged over the recent years, with large outbreaks worldwide. However, no specific vaccines and drugs against EV-D68 are available. Accumulating studies are extending our understanding on the pathogenesis of EV-D68. In this review, we summarized the research on EV-D68 receptors, hoping to provide a reference for the development of targeted antiviral drugs.