科微学术

微生物学通报

中药饮片有害微生物负载及鉴定技术研究进展
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基金项目:

国家重点研发计划(2017YFC1600403);广东省科学院实施创新驱动发展能力建设专项(2019GDASYL-0201001)


Progress on contamination and identification methods of harmful microorganisms in Chinese herbal medicines
Author:
  • CHEN Ling

    CHEN Ling

    Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Detection Center of Microbiology, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong, China;College of Food Science, South China Agricultural University, Guangzhou 510642, Guangdong, China
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  • CHEN Wei

    CHEN Wei

    Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Detection Center of Microbiology, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong, China
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  • LIU Zhenjie

    LIU Zhenjie

    Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Detection Center of Microbiology, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong, China
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  • ZENG Jiahui

    ZENG Jiahui

    Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Detection Center of Microbiology, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong, China
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  • GUO Weipeng

    GUO Weipeng

    Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Detection Center of Microbiology, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong, China
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  • WU Qingping

    WU Qingping

    Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Detection Center of Microbiology, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong, China
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  • ZHANG Jumei

    ZHANG Jumei

    Guangdong Provincial Key Laboratory of Microbial Safety and Health, State Key Laboratory of Applied Microbiology Southern China, Guangdong Detection Center of Microbiology, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong, China
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    摘要:

    中药饮片在种植、采收、加工和储藏等过程中均有可能受到多种微生物的污染,特别是有害微生物如致病细菌、产毒真菌等的存在会影响中药饮片的安全性。本文综述了近年来中药饮片有害微生物的污染情况,比较不同国家药典对中药饮片微生物限度和真菌毒素限量的差异,归纳当前用于不同微生物鉴定方法的适用性,以期为中药饮片质量安全研究工作提供参考。

    Abstract:

    Chinese herbal medicines may be contaminated with microorganisms (pathogenic bacteria and mycotoxigenic fungi) during cultivation, harvesting, processing, and storage, which causes spoilage and consequently affects the safety of herbal medicines. This study summarized the microbial contamination of common herbal medicines in recent years, and compared the limits of microbial and mycotoxin in pharmacopeias of different countries. Moreover, we reviewed the detection and identification methods of microorganisms in herbal medicines to provide a reference for similar research.

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引用本文

陈玲,陈维,刘振杰,曾嘉辉,郭伟鹏,吴清平,张菊梅. 中药饮片有害微生物负载及鉴定技术研究进展[J]. 微生物学通报, 2022, 49(7): 2838-2848

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历史
  • 收稿日期:2021-10-15
  • 录用日期:2021-12-04
  • 在线发布日期: 2022-07-06
  • 出版日期: 2022-07-20
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