中药饮片有害微生物负载及鉴定技术研究进展

Progress on contamination and identification methods of harmful microorganisms in Chinese herbal medicines

摘要:

中药饮片在种植、采收、加工和储藏等过程中均有可能受到多种微生物的污染，特别是有害微生物如致病细菌、产毒真菌等的存在会影响中药饮片的安全性。本文综述了近年来中药饮片有害微生物的污染情况，比较不同国家药典对中药饮片微生物限度和真菌毒素限量的差异，归纳当前用于不同微生物鉴定方法的适用性，以期为中药饮片质量安全研究工作提供参考。

Abstract:

Chinese herbal medicines may be contaminated with microorganisms (pathogenic bacteria and mycotoxigenic fungi) during cultivation, harvesting, processing, and storage, which causes spoilage and consequently affects the safety of herbal medicines. This study summarized the microbial contamination of common herbal medicines in recent years, and compared the limits of microbial and mycotoxin in pharmacopeias of different countries. Moreover, we reviewed the detection and identification methods of microorganisms in herbal medicines to provide a reference for similar research.