Abstract:Curriculum ideological and political education plays an important role in the "all-staff whole-process all-round education" system at colleges and universities, which is one of the hot spots in the current research on higher education reform. This article takes the course of Environmental Engineering Microbiology as an example to expound the ideological and political education practice. Firstly, it discussed the specific measures of ideological and political education from four aspects:exploring the ideological and political elements of the curriculum, improving teachers' ideological and political teaching ability, cultivating students' interest in learning, and important guarantees. Secondly, it demonstrated the effectiveness of curriculum ideological and political education practice from the aspects of improving students' ideological and political ideas, increasing students' curriculum scores, and leading the curriculum ideological and political education of the whole university. Finally, we discussed and prospected ideological and political education based on the teaching practice of Environmental Engineering Microbiology. Through the above research, it is expected to pave the way for the ideological and political education reform and provide a reference for giving play to the education mechanism of Environmental Engineering Microbiology.