Abstract:Specialized curriculum is the basic carrier of curriculum ideological and political education construction, which is the fundamental task of curriculum teaching reform. Medical Microbiology is a basic discipline for medical students, which involves the pathogenic microorganisms closely related to human life and thus is practical. The construction of curriculum ideological and political education system for Medical Microbiology should be carried out in close combination with the content of the discipline and human health needs. That is how we strengthen students' knowledge learning and ideological education and achieve the goal of "fostering virtue through education". This paper introduced the methods for the reform of ideological and political curriculum for Medical Microbiology, the promotion approaches, and the effect of the education, based on the content of the discipline and the principle of safeguarding people's health and striving for the interests of people. The methods for the reform included reconstructing knowledge, shooting teaching videos, and compiling 50 Educational Stories for Medical Students. The promotion approaches were handing out the book for free, improving the education quality based on the network teaching platform, and boosting the education by enhancing the guidance and communication. The reform has achieved ideal effect.