“发酵工程原理与技术”混合式教学研究与实践：以“抗生素发酵生产工艺与工程实践”内容为例

Mixed teaching of Principle and Technology of Fermentation Engineering: an example of process and practice of antibiotic production by fermentation

摘要:

“发酵工程原理与技术”是理工科高校生物专业的核心课程之一，具有较强的应用性和实践性。然而目前以线下教学为主的传统教学方式不利于学生对知识的理解和掌握。同时，该课程实验教学环节存在发酵设备更新不及时、缺乏大型工艺设备、易受场地限制等问题，严重影响实践教学效果。线上线下相结合的混合式教学模式是丰富教学资源和提升教学质量的重要手段。我们以“抗生素发酵生产工艺与工程实践”内容为例，基于虚拟仿真平台设计并构建虚拟仿真实验项目，同时结合课堂教学和实验室教学等线下教学方式，形成线上线下高度融合的混合式教学新模式。混合式教学强化了课堂教学与在线教学、虚拟实验与实体实验的有机结合，促进了学生扎实掌握理论知识和实验技能，培养了学生的创新精神和实践能力，提高了学生的综合素质。

Abstract:

Principle and Technology of Fermentation Engineering is a core course of Biology major in colleges and universities of science and engineering, which has been widely applied. Traditional teaching method mainly based on offline teaching is not conducive to students' mastery of knowledge. Additionally, there are some problems in the experimental teaching of this course, such as delay in updating fermentation equipment, lack of large-scale process equipment and site restrictions, which seriously affect the teaching quality. Hybrid teaching mode incorporating online and offline teaching is an important means to enrich teaching resources and improve teaching quality. Taking process and practice of antibiotic production by fermentation as an example, we constructed a virtual simulation experiment project on the basis of virtual simulation platform. In addition, combining offline teaching methods such as classroom teaching and laboratory teaching, we formed a new hybrid teaching mode highly integrating online and offline teaching. The hybrid teaching strengthened the organic combination of classroom teaching and online teaching, as well as virtual and physical experiment, which facilitated students' mastery of theoretical knowledge and experimental skills, cultivated their innovative spirit and practical ability, and improved their comprehensive quality.