Abstract:Curriculum ideology and politics is an important way of ideological and political education in universities in the new era. The history of science records the process from generation to sustainable development of scientific knowledge, which contains rich educational value and provides new perspectives and ideas for the ideological and political teaching of professional courses. In this study, we selected materials in four aspects of scientific spirit, scientific thinking, scientific interest, and scientific ethics from the rich educational values of history of science. Meanwhile, we reviewed the history of Nobel Prize related to Genetic Engineering. Then, taking the materials of the four aspects above as the carrier of education, we excavated the curriculum ideological and political elements contained in the history of Nobel Prize related to Genetic Engineering, and helps students achieve their goals in ideology and politics by carrying out the ideological and political education in the Genetic Engineering course. Finally, we employed questionnaire survey and in-depth interview to evaluate the teaching performance. With such teaching practice, we aim to guide students to establish the correct value concept and improve their ideological and political level, and to provide a reference for the construction of curriculum ideological and political system of biology courses.