基于肠道微生态的白术散作用机制研究进展

Research progress on the action mechanism of Baizhu powder based on intestinal microecology

摘要:

肠道作为人体消化吸收的重要场所，是人体最大的免疫器官，在维持正常生理活动中发挥着非常重要的作用。随着人类饮食的多元化，肠道菌群对健康的影响吸引了越来越多的关注。肠道微生态与免疫、代谢系统疾病和肿瘤等50多种疾病相关，同时疾病也会影响肠道菌群，通过饮食调节和用药会影响肠道菌群，进而影响健康。白术散是以食药两用药材为主的方剂，能够改善肠道微生态、健脾益气、和胃生津，进而达到调整人体健康的目的。近年来，诸多临床研究和动物试验在研究白术散治疗肠道菌群失调相关疾病方面取得了显著进展。本文就白术散对肠道微生态的作用机制进行总结，以期为临床研究白术散治疗肠道相关疾病提供一些理论依据和实验基础。

Abstract:

As an important organ for digestion and absorption, intestinal tract is the largest immune organ of human body and plays a very important role in maintaining normal physiological activities. With the diversification of human diet, more attention has been attracted about the impact of intestinal flora on health. Intestinal microecology is related to more than 50 diseases including immunity, metabolic system diseases, tumors and so on. There is no doubt that diseases can also affect the human intestinal flora. Baizhu powder is a prescription mainly composed of edible medicinal plant materials, which can improve the intestinal microecology, invigorate spleen and replenish Qi, promote the secretion of saliva or body fluid and reinforcing the stomach, to achieve the purpose of maintaining human health. In recent years, many clinical studies and animal experiments have made remarkable progress in the treatment of intestinal flora disorders related diseases with Baizhu powder. This paper summarizes the mechanism of Baizhu powder on intestinal microecology, in order to provide some theoretical and experimental basis for clinical research on Baizhu powder in the treatment of intestinal related diseases.